Postgraduate Pharmacy Personal Statement
I am interested in the Masters of Pharmacy (MPharm) Programme because I am interested in the modules on which it is based. I want to do the MPharm programme so as to extend my knowledge in Medicines. I would like to get a deeper understanding of how to formulate and administer drugs safely.
There is need to continually find new leads to innovative medicines to help combat diseases more efficiently, advancement in drug discovery and finding new technologies to improve drug delivery systems is something that interests me immensely and I would like to advance my education in that direction.
An Mpharm programme would be a rewarding course for me to undertake both personally and professionally. An MPharm programme would give me a wide range of opportunities and carrier options. It would give me professional independence where I can work with autonomy.
I would qualify for the Mpharm programme because I have recently completed BSc in pharmaceutical Science which has given me good understanding of how drugs work. The modules I have undertaken In my BSc Pharmaceutical Science will help me navigate successfully in the MPharm programme.
Modules such as Bioanalytical techniques gave me grounding for analytical techniques. I developed an understanding of the principles and terminology which is used in qualitative and quantitative, absolute and empirical methods, sampling, sample treatments, standards and calibration techniques.
I learnt a range of techniques for determining the amount of an element or compound in a specified sample, describe the theoretical background and instrumental requirements of these techniques.
These techniques included spectroscopic methods such as solution spectroscopy, Mass spectroscopy and the fragmentation for molecular analysis, atomic absorption spectroscopy, and infrared spectroscopy and UV/VIS spectroscopy. Separation methods such as High Performance Liquid Chromatography, gel filtration, thin layer chromatography (TLC) and gas chromatography.
Eletroanalytical techniques such as ion –sensitive electrodes, membrane systems, enzyme sensors and pH electrodes. I gained a better understanding of immunoassays such as radio immunoassays, enzyme-multiplied immunoassay technique and ELISA and their application in urine drug tests.
I developed the practical skills needed for sample preparation, instrument calibration and gained experience in handling analytical results. The Bioanalytical techniques modules helped me understand and select the application of appropriate analytical techniques and making valid interpretations of analyses.
Drug delivery systems helped me gain knowledge of the principles which describe and control the effective delivery of drugs from their delivery systems to target sites.
It gave me the understanding of the physicochemical properties- factors involved in the stabilisation of pharmaceuticals such as the kinetics of decomposition and the solubility in polar and non-polar solvents. I gained an appreciation of manufacturing processes and the stability of formulations in the overall development of new products.
How drugs exert their pharmacologic effects, how they get to the site of action and the properties they need to have for them to exert their effects. The drug design strategies that are employed to improve the physiochemical, pharmacokinetic and pharmacodynamics properties of the drugs through chemical transformations.
The ethical issues surrounding drug development and delivery mechanisms. Combination of principles of pharmacology, systems pharmacology gave me prescriptive knowledge into the drugs. They also gave me an understanding of drug actions through chemical mediators on specified organ systems and at cellular and molecular level. They gave me an understanding of drug toxicity and the side-effects the drugs may have on other organs.
Medicinal chemistry I have learnt about the relationships between the structure and the activity of drugs as well as assess critically the methodologies and strategies that govern whether or not a synthetic compound would be a good drug candidate for mass production. I learnt how to assess if differences between research methods and development of organic compounds looking at the whether the processes are economically and environmentally viable for scaling up.
Organic chemistry I have come to understand the interpretation of organic reactions in terms of generic mechanisms neutral, nucleoophilic and electrophilic and the different outcomes which are addition, elimination, substitution and rearrangement. This enabled me to be able to predict the outcomes of complex mechanistic processes making comparisons of the factors influencing one pathway from another.
I also learnt to interpret Nuclear Magnetic Resonance spectral data. In my biochemistry modules such metabolic biochemistry and clinical biochemistry module I gained an appreciation of the diversity and the interconnection of metabolic pathways, the use of different metabolites to screen diagnose and monitor diseases.
My project and practical work in my final year gave me valuable practice on how to behave in a laboratory including key areas such as health and safety and a basis for good laboratory practice. I gained valuable practice in advanced synthetic and purification techniques such as fractional, vacuum distillation and solvent extraction.
I also earned some valuable practice in High Performance Liquid Chromatography (HPLC), Mass spectrum, Gas chromatography. I am able to use and read out different spectra which include UV Visible and NMR.
My personal statement shows what i have learnt in the past three years and how the BSc pharmceutical Science has increased my interest in medicines. I would like to enhance my knowledge and an MPharm would give me that opportunity. It shows the modules i have completed and shows that i am well equipped and qualified to undertake the MPharm programme